Please use this identifier to cite or link to this item: http://dspace.azti.es/handle/24689/1634
Files in This Item:
There are no files associated with this item.
Full metadata record
DC FieldValueLanguage
dc.contributor.authorNzioka, Anthony-
dc.contributor.authorValencia, Ainara-
dc.contributor.authorAtxaerandio-Landa, Aitor-
dc.contributor.authorDiaz de Cerio, Oihane-
dc.contributor.authorAmzad Hossain, Mohammad-
dc.contributor.authorKorta, Maria-
dc.contributor.authorOrtiz-Zarragoitia, Maren-
dc.contributor.authorCancio, Ibon-
dc.date.accessioned2023-10-04T10:45:09Z-
dc.date.available2023-10-04T10:45:09Z-
dc.date.issued2023-
dc.identifierWOS:000901510300002-
dc.identifier.issn0141-1136-
dc.identifier.urihttp://dspace.azti.es/handle/24689/1634-
dc.description.abstractFollicular atresia is an energy-saving oocyte resorption process that can allow the survival of female fish when environmental conditions are unfavourable and at the expense of fecundity. This study investigated the tran-scription levels of apoptosis and autophagy-related genes during atresia in the European hake that can show episodes of increased follicular atresia throughout the reproductive cycle. 169 female individuals were collected from the Bay of Biscay, and the ovaries were analysed using histological and molecular methods. Different levels of atresia were histologically detected in 73.7\% of the ovaries analysed and the TUNEL assay identified apoptotic nuclei in follicles from both previtellogenic and vitellogenic stages. Transcripts of beclin-1 and ptenb were up -regulated in the ovaries containing atretic follicles, whereas p53, caspase-3, cathepsin D and dapk1 were up -regulated only in ovaries presenting vitellogenic atretic follicles. Our results indicate different implications of apoptotic vs autophagic processes leading to atresia during oocyte development, vitellogenesis being the moment of maximal apoptotic and autophagic activity in atretic hakes. The analysed genes could provide early warning biomarkers to identify follicular atresia in fish and evaluate fecundity in fish stocks.-
dc.language.isoEnglish-
dc.publisherELSEVIER SCI LTD-
dc.subjectApoptosis-
dc.subjectAutophagy-
dc.subjectBiomarker-
dc.subjectEuropean hake-
dc.subjectFisheries-
dc.subjectFollicular atresia-
dc.subjectmRNA-
dc.subjectReproductive cycle-
dc.subjectRIBOSOME BIOGENESIS-
dc.subjectFISH OVARY-
dc.subjectCOMPLEX-
dc.subjectGROWTH-
dc.subjectRNA-
dc.subjectDISRUPTION-
dc.subjectREGRESSION-
dc.subjectOOGENESIS-
dc.subjectFOLLICLES-
dc.subjectEVOLUTION-
dc.titleApoptosis and autophagy-related gene transcription during ovarian follicular atresia in European hake (Merluccius merluccius)-
dc.typeArticle-
dc.identifier.journalMARINE ENVIRONMENTAL RESEARCH-
dc.format.volume183-
dc.contributor.funderSpanish Ministry of Science, Innovation and Universities [AGL2015-63936-R, PGC2018-101442-B-I00]-
dc.contributor.funderBasque Government [IT1302-19]-
dc.contributor.funderUniversity of the Basque Country (UPV/EHU)-
dc.identifier.e-issn1879-0291-
dc.identifier.doi10.1016/j.marenvres.2022.105846-
Appears in Publication types:Artículos científicos



Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.