Please use this identifier to cite or link to this item:
Files in This Item:
There are no files associated with this item.
Title: Natural Killers: Opportunities and Challenges for the Use of Bacteriophages in Microbial Food Safety from the One Health Perspective
Authors: Lavilla, Maria; Domingo-Calap, Pilar; Sevilla-Navarro, Sandra;; Lasagabaster, Amaia
Abstract: Ingestion of food or water contaminated with pathogenic bacteria may cause serious diseases. The One Health approach may help to ensure food safety by anticipating, preventing, detecting, and controlling diseases that spread between animals, humans, and the environment. This concept pays special attention to the increasing spread and dissemination of antibiotic-resistant bacteria, which are considered one of the most important environment-related human and animal health hazards. In this context, the development of innovative, versatile, and effective alternatives to control bacterial infections in order to assure comprehensive food microbial safety is becoming an urgent issue. Bacteriophages (phages), viruses of bacteria, have gained significance in the last years due to the request for new effective antimicrobials for the treatment of bacterial diseases, along with many other applications, including biotechnology and food safety. This manuscript reviews the application of phages in order to prevent food- and water-borne diseases from a One Health perspective. Regarding the necessary decrease in the use of antibiotics, results taken from the literature indicate that phages are also promising tools to help to address this issue. To assist future phage-based real applications, the pending issues and main challenges to be addressed shortly by future studies are also taken into account.
Issue Date: 2023
Publisher: MDPI
Type: Review
DOI: 10.3390/foods12030552
E-ISSN: 2304-8158
Funder: CDTI (Spain), under the Programa para Centros Tecnologicos de Excelencia ``Cervera�� [CER-20211010]
Ramon y Cajal contract [RYC2019-028015-I]
Generalitat Valenciana-Fondo Social Europeo
Appears in Publication types:Artículos científicos

Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.